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Link: Cognitive and affective dysfunctions in autoimmune thyroiditis

Hashimoto’s thyroiditis (HT) is the most frequent cause of hypothyroidism in areas with sufficient iodine intake. While the impact of thyroid function on mood and cognition is well known, only in the recent years, an increasing number of studies report on the association of HT with cognitive and affective disturbances also in the euthyroid state. Recent imaging studies have shown that these impairments are accompanied by altered brain perfusion, in particular, in the frontal lobe and a reduced gray matter density in the left inferior gyrus frontalis. Brain function abnormalities in euthyroid patients with HT may be subtle and only detected by specific testing or even severe as it is the case in the rare neuropsychiatric disorder Hashimoto’s encephalopathy (HE).

 

The full text could not be located; however, the abstract can be found at http://www.sciencedirect.com/science/article/pii/S0889159114000749.

Copyright © 2014 Elsevier Inc. All rights reserved.

 

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