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Link: Psychiatric autoimmunity: NMDA-Receptor-IgG and Beyond

Background

Descriptions of psychiatric autoimmunity beyond NMDA-R encephalitis are sparse.

Objective

To report the autoimmune psychiatric spectrum currently recognized in Mayo Clinic practice.

Methods

Chart review, testing of stored serum and CSF for IgGs reactive with synaptic receptors and ion channels, neuronal nuclear and cytoplasmic antigens (including GAD65), and case-control comparison. Patients were: Group 1, all adult psychiatric inpatients tested for neural autoantibodies (2002-2011; n=213); Group 2, all Mayo NMDA-receptor-IgG-positive patients (2009-2013; n=13) and healthy control subjects (n=173).

 

At this time, only the abstract is available online. It can be found at http://www.sciencedirect.com/science/article/pii/S0033318215000043.

Copyright © 2015 Published by Elsevier Inc.

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