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Link: What is AE?

What other medications are commonly prescribed to patients with AE? Are there any medications that specifically should not be taken by someone suffering from AE?

Treatment of symptoms – in particular agitation and sleeplessness, using benzodiazepines is common and appropriate. High-dose Lorazepam (trademark: Ativan) is highly effective for AE patients.

Note that because of the completely different disease mechanism, use of anti-psychotic drugs commonly used to treat bipolar disorder and schizophrenia such as Clozapine (Clozaril) and Risperidone (Risperidal) may not be effective, and may actually increase the severity of AE symptoms.

Because individuals with undiagnosed AE are commonly misdiagnosed as having bipolar disorder or schizophrenia, clinicians and families should be alert to possible deterioration or severe negative reactions in patients receiving this class of drugs.

Failure to respond to anti-psychotics can be a diagnostic clue that the actual cause of psychosis may be autoimmune encephalitis.


This page on shares some frequently asked questions on Autoimmune Encephalopathy. Particularly of interest is the above section and more about psychiatric manifestations in AE patients.


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