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Link: Autoimmune Encephalopathy

Clinical Presentation and Demographics

Autoimmune encephalopathies, like most autoimmune syndromes, are more common in women than in men. Many of the pathogenic antibody and paraneoplastic forms occur in young adults, but the nonspecific forms occur more frequently in middle-aged and older individuals. The clinical and demographic features of 46 patients with confirmed autoimmune encephalopathy in a recent large series are outlined in Table 2.[9] Their mean age was 59 years (± 12.1 years). Onset was subacute (over 1 to 6 weeks) in 93%, and 91% experienced marked fluctuations. A coexisting systemic autoimmune disorder was present in 48% (Table 3).

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Copyright © Medscape 2015 | Published in Seminars in Neurology

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