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Link: Rethinking therapy decisions in autoimmune encephalopathy

Researchers say that diagnosis and management of encephalopathies may need to be rethought, as many patients who test negative for the relevant antibody still benefit from immunotherapy.

Of 48 patients with a diagnosis of probable autoimmune encephalopathy, only 21 (44%) individuals were positive for antibodies known to be associated with this type of encephalopathy. However, both antibody-positive and antibody-negative patients responded to immunotherapy, with complete recovery achieved in 20 (42%) children, after a mean follow-up period of 24 months.

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