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Link: Woman Falls Suddenly Ill After Developing Autoimmune Encephalitis

Keely Shaw, 27, was feeling tired and getting a lot of headaches after breaking up with her boyfriend of 11 months. Chalking up her apparent illness to heartbreak, she left her home in Pontefract in the English county of West Yorkshire and went on a day trip to London in November 2013.

This young woman went on to experience sudden personality changes and seizures which lead to an anti-NMDA receptor encephalitis diagnosis in the UK. The full article can be found at http://www.opposingviews.com.

Copyright © January 25th, 2015 | Author Amanda Andrade-Rhoades

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Effects of Step-Wise Increases in Dietary Carbohydrate on Circulating Saturated Fatty Acids and Palmitoleic Acid in Adults with Metabolic Syndrome

Recent meta-analyses have found no association between heart disease and dietary saturated fat; however, higher proportions of plasma saturated fatty acids (SFA) predict greater risk for developing type-2 diabetes and heart disease. These observations suggest a disconnect between dietary saturated fat and plasma SFA, but few controlled feeding studies have specifically examined how varying saturated fat intake across a broad range affects circulating SFA levels.

Posted by G.D. on 25th November, 2014. The full study can be found at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113605.

Copyright © 2014 Volk et al.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy-proven European multicentre study.

The objective of this study was to investigate the value of serum (blood) “anti-tissue” transglutaminase IgA antibodies and IgA antiendomysial antibodies in the diagnosis of Coeliac (Celiac) Disease in a group of subjects in Europe.

This abstract only link was posted by G.D. on 19th November, 2014. The abstract can be found at http://europepmc.org/abstract/MED/15647647.

© Authors | Colin P., et al

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Molecular and cellular mechanisms underlying anti-neuronal antibody mediated disorders of the central nervous system

Over the last decade multiple autoantigens located on the plasma membrane of neurons have been identified. Neuronal surface antigens include molecules directly involved in neurotransmission and excitability. Binding of the antibody to the antigen may directly alter the target protein’s function, resulting in neurological disorders.

This was shared by G.D. on 16th  November, 2014. The abstract only can be found at http://www.sciencedirect.com/science/article/pii/S1568997213002115.

© 2013 Elsevier B.V. All rights reserved

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Th17 Response and Inflammatory Autoimmune Diseases

The proinflammatory activity of T helper 17 (Th17) cells can be beneficial to the host during infection. However, uncontrolled or inappropriate Th17 activation has been linked to several autoimmune and autoinflammatory pathologies. Indeed, preclinical and clinical data show that Th17 cells are associated with several autoimmune diseases such as arthritis, multiple sclerosis, psoriasis, and lupus. Furthermore, targeting the interleukin-17 (IL-17) pathway has attenuated disease severity in preclinical models of autoimmune diseases. Interestingly, a recent report brings to light a potential role for Th17 cells in the autoinflammatory disorder adult-onset Still’s disease (AOSD). Whether Th17 cells are the cause or are directly involved in AOSD remains to be shown. In this paper, we discuss the biology of Th17 cells, their role in autoimmune disease development, and in AOSD in particular, as well as the growing interest of the pharmaceutical industry in their use as therapeutic targets.

Copyright © 2012 Janelle C. Waite and Dimitris Skokos. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study was posted on 28th October, 2014 by G.D. to this thread – https://www.facebook.com/groups/564512313648230/permalink/589270541172407/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Overview of the Cranial Nerves

Twelve pairs of nerves—the cranial nerves—lead directly from the brain to various parts of the head, neck, and trunk. Some of the cranial nerves are involved in the special senses (such as seeing, hearing, and taste), and others control muscles in the face or regulate glands. The nerves are named and numbered (according to their location, from the front of the brain to the back).

The full Merc Manuals “Consumer Version” can be found at http://www.merckmanuals.com/home/brain-spinal-cord-and-nerve-disorders/cranial-nerve-disorders/overview-of-the-cranial-nerves.

Copyright © Merc Manuals

This link was posted on 4th November, 2014 by J.J. to the thread https://www.facebook.com/groups/251477975360/permalink/10154754360385361/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Be Wary of “Fad” Diagnoses

A small percentage of physicians and large percentages of chiropractors, naturopaths and bogus “nutritionists” are labeling patients with diagnoses not recognized by the scientific community. Some of these practitioners apply one or more of these diagnoses to almost every patient they see. The health-food industry profits from this process by selling books promoting these alleged conditions and supplement concoctions claimed to help them. Some “fad” diagnoses have been around for years, while others are recent creations.

This article by Dr. Stephen Barrett, MD talks about “fad” diagnoses.

Copyright © Author

This article was posted by G.D. to the thread https://www.facebook.com/groups/251477975360/permalink/10154719116285361/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Hashimoto’s encephalopathy : epidemiology, pathogenesis and management.

Hashimoto’s encephalopathy is a term used to describe an encephalopathy of presumed autoimmune origin characterised by high titres of antithyroid peroxidase antibodies. In a similar fashion to autoimmune thyroid disease, Hashimoto’s encephalopathy is more common in women than in men. It has been reported in paediatric, adult and elderly populations throughout the world. The clinical presentation may involve a relapsing and remitting course and include seizures, stroke-like episodes, cognitive decline, neuropsychiatric symptoms and myoclonus.

The full text of this study can be found at http://www.ncbi.nlm.nih.gov/pubmed/17850170.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Dr. David Edelberg – Internal Medicine

Dr. Edelberg, board certified in Internal Medicine in 1974, began incorporating alternative therapies into his practice during the 1980’s. Since founding the parent company of WholeHealth Chicago in 1993, he has become nationally recognized as one of the pioneers of integrative medicine, a new specialty combining conventional medicine with alternative therapies. Author of numerous articles and editor of five books on integrative medicine; look for his latest book, “Healing Fibromyalgia” and “The Triple Whammy Cure”.

To read more about Dr. Edelberg, you can find his profile at http://wholehealthchicago.com/about/david-edelberg/.  This link was posted by S.L. to a thread on 27th October, 2014 https://www.facebook.com/groups/251477975360/permalink/10154713089475361/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link PDF: Autoantibodies associated with diseases of the CNS: new developments and future challenges

Several CNS disorders associated with specifi c antibodies to ion channels, receptors, and other synaptic proteins have been recognised over the past 10 years, and can be often successfully treated with immunotherapies. Antibodies to components of voltage-gated potassium channel complexes (VGKCs), NMDA receptors (NMDARs), AMPA receptors (AMPARs), GABA type B receptors (GABABRs), and glycine receptors (GlyRs) can be identifi ed in patients and are associated with various clinical presentations, such as limbic encephalitis and complex and diff use encephalopathies. These diseases can be associated with tumours, but they are more often non-paraneoplastic, and antibody assays can help with diagnosis. The new specialty of immunotherapy-responsive CNS disorders is likely to expand further as more antibody targets are discovered. Recent fi ndings raise many questions about the classifi cation of these diseases, the relation between antibodies and specifi c clinical phenotypes, the relative pathological roles of serum and intrathecal antibodies, the mechanisms of autoantibody generation, and the development of optimum treatment strategies.

This article by Angela Vincent, Christian Bien, Sarosh Irani, and Patrick Waters talks about conditions of the CNS caused by autoantibodies. The full paper can be found at ResearchGate.net. This was posted to thread https://www.facebook.com/groups/251477975360/permalink/10154711712105361/ on 27th October, 2014 by G.D.

Copyright © The Lancet 2011 | Authors Angela Vincent, Christian Bien, Sarosh Irani, and Patric Waters

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.