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Published 2014

  • Link: The use of plasma exchange in Hashimoto's encephalopathy: A case report and review of the literature.
    Hashimoto’s Encephalopathy (HE) is a very rare condition characterized by psychosis, seizures, cognitive fluctuations, and myoclonus. In a few published cases, plasma exchange has been used due to the theoretical removal of antithyroid peroxidase antibodies (anti-TPO), one of the postulated causes of the condition.   The abstract can be found at unboundmedicine.com; however, the full […]
  • Link: Pediatric Hashimoto's encephalopathy with peripheral nervous system involvement
    Hashimoto encephalopathy is a syndrome of encephalopathy associated with elevated concentration of circulating serum anti-thyroid antibodies usually responsive to steroid therapy. We report a 13-year-old girl with Hashimoto encephalopa- thy and peripheral nervous system involvement. The child had experienced high-grade pyrexia, global headache and sleeplessness. After admission she had an ileus with a distended urinary […]
  • Link: Catatonia: A Duel of Hashimoto’s Encephalopathy and Anti NMDA Receptor Encephalitis (P5.166)
    OBJECTIVE To present a unique case of diagnostic conundrum in a catatonic patient positive for both anti NMDA receptor and anti TPO antibodies with a normal 24 hour EEG, brain MRI and CSF.BACKGROUND:Catatonia, although typically associated with schizophrenia and other affective disorders, can be an uncommon presenting feature of two rare neurologic disorders: Hashimoto’s encephalopathy […]
  • Link: Severe complication of catatonia in a young patient with Hashimoto's encephalopathy comorbid with Cornelia de Lange syndrome
    Dear Editor, Cornelia de Lange syndrome (CdLs) is a rare genetic disease diagnosed as a cluster of symptoms; however, there are only a few reports mentioning the immunologic problems in patients with CdLs. Hashimoto’s encephalopathy (HE) is an autoimmune encephalitis, which manifests as neurocognitive impairment and elevated antithyroid antibody (ATA) titers. Childhood HE manifests especially […]
  • Link: Hashimoto's Encephalopathy - A Brief Review
    Hashimoto’s encephalopathy (HE) is a syndrome of altered mental status, hallucinations, delusional thinking, and often, epileptic seizures. It is diagnosed by the clinical syndrome, the presence of elevated titers of antithyroid antibodies, the lack of another diagnosis based on clinical evaluation, and the response to corticosteroid and other immunosuppressant treatment. This review discusses the symptoms, […]
  • Link: Hashimoto’s encephalopathy mimicking presenile dementia
    Abstract Hashimoto’s encephalopathy (HE), which carries kaleidoscopic clinical presentations, is easily misdiagnosed in clinical practice. Early diagnosis and prompt initiation of steroid therapy are associated with good prognosis. We describe a 50-year-old female patient who had subclinical hypothyroidism and who presented herself with gradual cognitive impairment, accompanied with auditory hallucination and delusion. Increased anti-thyroid antibodies […]
  • Link: Anti-NMDAR encephalitis misdiagnosed as Hashimoto's encephalopathy
    Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a well-defined autoimmune disorder. Hashimoto’s encephalopathy (HE) is a still controversial entity, lacking definite diagnostic criteria. This study discusses a paediatric case of Autoimmune Encephalopathy with presentation similar to Hashimoto’s Encephalitis. The abstract only can be found at http://www.sciencedirect.com/science/article/pii/S1090379813001256. This article is only available by subscription or purchase.   Copyright © 2013 […]
  • Link: A Case of Refractory Hashimoto’s Encephalopathy Demonstrating Improvement with Plasmapheresis (P5.227)
    Objective To describe an unusual case of Hashimoto’s encephalopathy (HE) associated with significant imaging findings that responded to plasmapheresis. Background Hashimoto’s thyroiditis was first described by Hakaru Hashimoto in 1912 but it was Lord Brain who first noted the association between thyroiditis and an unusual encephalopathy in 1966 that he called Hashimoto’s encephalopathy. As it […]
  • Link: Hashimoto's Encephalopathy Complicated by Cerebellar Ataxia: A Case Report

    To present a case of Hashimoto’s Encephalopathy (HE) with long-term neurological sequelae.BACKGROUND: Hashimoto’s Encephalopathy, also known as steroid responsive encephalopathy secondary to autoimmune thyroiditis (SREAT), is a rare condition that typically affects middle aged females with known anti-TPO antibodies and a history of Hashimoto’s thyroiditis. The diagnosis is often overlooked because there is no diagnostic biomarker, and patients can present with several non-specific neurological symptoms that are often incorrectly attributed to other disease processes. Neurological outcomes are rarely reported. It is important to recognize and distinguish HE from other encephalopathies as it is a distinct, treatable entity, which is almost always responsive to steroid therapy.

  • Link: A follow-up 18F-FDG brain PET study in a case of Hashimoto's encephalopathy causing drug-resistant status epilepticus treated with plasmapheresis

    Hashimoto’s encephalopathy (HE) is a rare neuropsychiatric syndrome associated with antithyroid antibodies. It may have an acute onset (episodes of cerebral ischemia, seizure, and psychosis) or it may present as an indolent form (depression, cognitive decline, myoclonus, tremors, and fluctuations in level of consciousness). We here describe a case of encephalopathy presenting as non-convulsive status epilepticus associated with Hashimoto’s thyroiditis (HT), unresponsive to corticosteroid therapy, with improvement after plasma exchange treatment.

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