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Paraneoplastic Antibodies

Purkinje cell antibodies, Neuronal antibodies

A family of autoantibodies recognising antigens in the brain which are associated with a variety of neurological manifestations occurring as a result of malignancy, usually ovarian or small cell carcinoma of the lung. The autantibodies may also recognise the tumour. Patients present with paraneoplastic cerebellar degeneration usually triggering a search for a previously unsuspected malignancy.There are several groups of autantibodies.

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