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Antibody

Link: Molecular and cellular mechanisms underlying anti-neuronal antibody mediated disorders of the central nervous system

Over the last decade multiple autoantigens located on the plasma membrane of neurons have been identified. Neuronal surface antigens include molecules directly involved in neurotransmission and excitability. Binding of the antibody to the antigen may directly alter the target protein’s function, resulting in neurological disorders.

This was shared by G.D. on 16th  November, 2014. The abstract only can be found at http://www.sciencedirect.com/science/article/pii/S1568997213002115.

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