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Link: Autoimmune Encephalitis

Abstract:

The term autoimmune encephalitis is used to describe a group of disorders characterised by symptoms of limbic and extra-limbic dysfunction occurring in association with antibodies against synaptic antigens and proteins localised on the neuronal cell surface. in recent years there has been a rapidly expanding knowledge of these syndromes resulting in a shift in clinical paradigms and new insights into pathogenic mechanisms. Since many patients respond well to immunosuppressive treatment, the recognition of these disorders is of utmost importance. in general, there are no brain-imaging modalities or biomarkers specific of these disorders other than the demonstration of the neuronal antibodies. a disease classification based on these antibodies provides information on prognosis and paraneoplastic aetiology. This article focuses on recent clinical advances, newly characterised antibodies and treatment approaches to these disorders.

The full text to this study by Frank Leypoldt, Klaus-Peter Wandinger, Christian Bien, and Josp Dalmau, can be found at http://www.touchneurology.com/articles/autoimmune-encephalitis.

This study was posted by G.D. on 31st October to this tread – https://www.facebook.com/groups/251477975360/permalink/10154711691935361/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Toxicities of Immunosuppressive Treatment of Autoimmune Neurologic Diseases

In parallel to our better understanding of the role of the immune system in neurologic diseases, there has been an increased availability in therapeutic options for autoimmune neurologic diseases such as multiple sclerosis, myasthenia gravis, polyneuropathies, central nervous system vasculitides and neurosarcoidosis. In many cases, the purported benefits of this class of therapy are anecdotal and not the result of good controlled clinical trials.

 

The full text can be found at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151601/.

 

Copyright © 2011 Bentham Science Publishers | by Enrico C Lallana and Camilo E Fadul

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

PDF Link: Autoimmune encephalitis – History & current knowledge

This PDF link will take you to a PDF published by PANDAS Network and has a wealth of information about auto-immune diseases.

 

Introduction
The acute fulminating epidemic form of encephalitis lethargica (von Economo, EL) seems to have
disappeared, since there have been no further reported epidemics after 1916-1927. During that period of
time, both rheumatic fever (RF) and Sydenham chorea (SC) were associated with and later proven to be
provoked by streptococcal infections. The occurrence of RF including SC has become much less frequent in
the industrial world.

The full text can be found in a PDF at http://pandasnetwork.org/wp-content/uploads/2013/07/Autoimmune_encephalitis.pdf

 

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: AutoImmune Encephalitis: Common Symptoms and Diagnostic Workup

An excellent technical video (caution: jargon heavy) which discusses Anti-NMDAR Encephalitis and it’s diagnosis and tretament. Highly recommended viewing for those who are pending a diagnosis of Autoimmune Encephalopathy of any kind as this provides some good information.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Autoimmune Encephalopathy

This MedScape article in “seminars in neurology”, written by Eoin P. Flanagan, M.B.B.Ch., Richard J. Caselli, M.D. for the Department of Neurology, Mayo Clinic, Rochester, Minnesota; and Department of Neurology, Mayo Clinic, Scottsdale, Arizona., and discusses non-paraneoplastic encephalopathy. It focuses on the global effects of auto-immune encephalopathy laboratory testing, imaging tools, anti-body testing, ruling out cancerous causes, and ruling out CJD, among other topics.

http://www.medscape.com/viewarticle/743774

The full text of this article is found at MedScape and was published in 2011. © 2011 Thieme Medical Publishers

 

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Voltage-gated Potassium Channel-complex Antibody-associated Limbic Encephalitis

This article discusses antibodies which target the voltage-gated potassium channel complex in the brain. This auto-immune condition effects twice as many men as women, unlike many other auto-immune diseases. It can present with forgetfulness, drowsiness, mood disorders, and generalised or faciobrachial seizures.

The article can be found at http://www.encephalitis.info/information/types-of-encephalitis/types-of-autoimmune-encephalitis/voltage-gated-potassium-channel-complex-antibody-associated-limbic-encephalitis/.

The full text of this article is found at Encephalitis.info and was published in 2014. Copyright © 2014 By Dr Thomas Miller,Clinical Research Fellow, University of Oxford, John Radcliffe Hospital, Oxford

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Autoimmune Encephalitis © Touch MEdical MEdia 2013 Autoimmune Encephalitis—Antibody Targets and Their Potential Pathogenicity in Immunotherapy-responsive Syndromes

This study discusses the role of antibodies which attack the brain’s neurons, thus causing amnesia, confusion, and seizures. It suggests that Autoimmune Encephalitis should be included in the differential diagnosis for conditions that include these symptoms.

The article can be found at https://www.academia.edu/5228749/Autoimmune_Encephalitis_Touch_MEdical_MEdia_2013_Autoimmune_Encephalitis-Antibody_Targets_and_Their_Potential_Pathogenicity_in_Immunotherapy-responsive_Syndromes.

This article is found at Academia.org. Copyright © 2013

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.