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Link: Autoimmune Dementia Study

Dr Sean Pittock, MD, a consultant in the Division of MS and Autoimmune Neurology at the Mayo Clinic discusses the findings of a recent study investigating the clinical predictors of immunotherapy responsiveness in patients with presumed Autoimmune Dementia. Available at:http://tinyurl.com/cq95c85

This video from Mayo Proceedings, “the world’s fourth largest medical journal”. Dr. Sean Pittock speaks more to this topic in another Mayo Labratories video on youtube.com.

This video link was posted to comments by G.D. on a post to Autoimmune Encephalitis (All types including Hashimoto’s Encephalopathy) on 2nd June, 2015.

 


 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Mild Cognitive Impairment – Ten Years Later

You can read the full test of the study he talks about at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081688/.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Evaluating Autoimmune Encephalopathies, Dementias, and Epilepsies

August 2014

A number of disorders of the central nervous system previously considered neurodegenerative and untreatable are now recognized as having a treatable autoimmune cause. Improved recognition is facilitated by an expanding profile of neural-specific autoantibodies and when detected in serum or cerebrospinal fluid, these IgG biomarkers reliably predict an autoimmune cause for neurological dysfunction in patients presenting with rapidly progressive brain disorders. New testing profiles relevant to the evaluation of autoimmune encephalopathy, dementia, and epilepsy are now available at Mayo Clinic.

The video and full text can be found at http://www.mayomedicallaboratories.com/. The original post comes from G.D. on 28th August, 2014.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Jay A. Van Gerpen, MD

Dr. Van Gerpen works in collaboration with colleagues at Mayo Clinic in Florida who are investigating the genetics of patients with Parkinson’s disease and other movement disorders. His role as a clinician is to recognize such patients and provide relevant biological samples to collaborators in genetics, neuropathology, basic neuroscience and other related areas.

The full profile for Dr. Van Gerpen can be found at http://www.mayo.edu/research/faculty/van-gerpen-jay-a-m-d/bio-00084969.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Paraneoplastic Autoantibody Evaluation, Serum

Serological evaluation of patients who present with a subacute neurological disorder of undetermined etiology, especially those with known risk factors for cancer

  • Directing a focused search for cancer
  • Investigating neurological symptoms that appear in the course of, or after, cancer therapy, and are not explainable by metastasis
  • Differentiating autoimmune neuropathies from neurotoxic effects of chemotherapy
  • Monitoring the immune response of seropositive patients in the course of cancer therapy
  • Detecting early evidence of cancer recurrence in previously seropositive patients

This page gives detailed information on Mayo Clinic’s PVAL or paraneoplastic autoantibody testing via blood, known as  serum, testing. All the information and antibodies tested for can be found at http://www.mayomedicallaboratories.com/test-catalog/Overview/83380.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: PET (Positron Emission Tomography) Scan: About your Mayo Clinic Test

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Spinal Tap / LP (Lumbar Puncture) – About your Mayo Clinic Test

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: EEG (Electroencephalogram) & EMU (Epilepsy Monitoring Unit) – About your Mayo Clinic Test

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Autoimmune Epilepsy Clinical Characteristics and Response to Immunotherapy

Due to JAMA rules, we cannot share any text from the article to give you an overview. However, the full text can be found at http://archneur.jamanetwork.com/article.aspx?articleID=1149705.

Copyright © 2014 American Medical Association

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Psychiatric autoimmunity: NMDA-Receptor-IgG and Beyond

Background

Descriptions of psychiatric autoimmunity beyond NMDA-R encephalitis are sparse.

Objective

To report the autoimmune psychiatric spectrum currently recognized in Mayo Clinic practice.

Methods

Chart review, testing of stored serum and CSF for IgGs reactive with synaptic receptors and ion channels, neuronal nuclear and cytoplasmic antigens (including GAD65), and case-control comparison. Patients were: Group 1, all adult psychiatric inpatients tested for neural autoantibodies (2002-2011; n=213); Group 2, all Mayo NMDA-receptor-IgG-positive patients (2009-2013; n=13) and healthy control subjects (n=173).

 

At this time, only the abstract is available online. It can be found at http://www.sciencedirect.com/science/article/pii/S0033318215000043.

Copyright © 2015 Published by Elsevier Inc.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.