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Link: Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients’ antibodies react with the N-terminal domain of the GluN1 (previously known as NR1) subunit of NMDAR causing in cultured neurons a selective and reversible internalization of cell-surface receptors. –


This was shared by G.D. on 25th November, 2014. To read the full text, proceed to

The full text of this article is found at Oxford University Press and was published in May of 2011. Copyright © 2014 Oxford University Press

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