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Link: Iron in Chronic Brain Disorders: Imaging and Neurotherapeutic Implications

Iron is important for brain oxygen transport, electron transfer, neurotransmitter synthesis, and myelin production. Though iron deposition has been observed in the brain with normal aging, increased iron has also been shown in many chronic neurologic disorders including Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. In vitro studies have demonstrated that excessive iron can lead to free radical production, which can promote neurotoxicity. However, the link between observed iron deposition and pathologic processes underlying various diseases of the brain is not well understood. It is not known whether excessivein vivo iron directly contributes to tissue damage or is solely an epiphenomenon. In this article we focus on the imaging of brain iron and the underlying physiology and metabolism relating to iron deposition. We conclude with a discussion of the potential implications of iron-related toxicity to neurotherapeutic development.

The full study can be found at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963417/. Posted by G.D. on 24th April 2015.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Scientists discover how to ‘switch off’ autoimmune diseases

Summary:

Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. Rather than the body’s immune system destroying its own tissue by mistake, researchers have discovered how cells convert from being aggressive to actually protecting against disease

 

This post from D.C. on 3rd September, 2014  shares research done by the University of Bristol on fighting autoimmune disease by revealing how to stop the cells from attacking healthy tissue. You can read the entire article at ScienceDaily.com.

Copyright © ScienceDaily

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Dr. Maria Isabel Leite

A public listing of publications authored by Dr. Maria Isabel Leite.

http://www.pubfacts.com/author/Maria+Isabel+Leite

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Dr. Nicolas C. Silver

Dr Silver qualified in Medicine in 1989 and trained to Registrar level in general medicine prior to specializing in Neurology. His PhD involved 4 years of dedicated research at the NMR Research Unit, Institute of Neurology (Queen Square, London) investigating magnetic resonance imaging techniques to evaluate and understand (1) inflammatory neurological disorders such as multiple sclerosis, (2) neurotoxic brain disorders, (3) primary headache disorders, and (4) neuropsychiatric disorders. His clinical neurology training took place at the National Hospital for Neurology and Neurosurgery, Queen Square and Barts and the London NHS Trust.

 

His full NHS profile can be found at The Spire Health Centre where he runs a clinic on headache/migraine. He also consults on other neurological conditions but his specialist interest is in “non-headache migraine symptoms”.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Spinal Tap / LP (Lumbar Puncture) – About your Mayo Clinic Test

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: 6 Signs You Have An Autoimmune Disease

Lupus. Multiple sclerosis. Hashimoto’s thyroiditis. Sjogren’s syndrome. Rheumatoid arthritis. Autoimmune hepatitis. Celiac disease. Crohn’s disease. Juvenile-onset diabetes. Most people are surprised to learn that these are all examples of autoimmune diseases.

 

The full article can be found at http://blackdoctor.org/1508/what-is-autoimmune-disease/.

Copyright © 2015, BlackDoctor, Inc . All Rights Reserved

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Dr. Joel Oger

Joel Oger

Docteur en mèdecine
Professor emeritus

A list of citations by Dr. Joel Oger can be found here at his http://www.researchgate.net profile.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Acquired pendular nystagmus with oscillopsia in multiple sclerosis: a sign of cerebellar nuclei disease

SYNOPSIS

In an unselected series of 644 cases of multiple sclerosis, 25 cases with acquired pendular nystagmus were found. Ten additional cases of pendular nystagmus in multiple sclerosis were investigated, and four cases from the literature are analysed. Acquired pendular nystagmus is purely sinusoidal in form, ceases with eye closure, is accompanied by oscillopsia, often monocular and vertical in direction, and never accompanied by optokinetic inversion. This is different from congenital nystagmus. Acquired pendular nystagmus in multiple sclerosis shows a high correlation with holding tremor of head and arm and with trunk ataxia, and must therefore be viewed as a result of lesions of cerebellar nuclei or their fibre connections with the brain-stem. Supporting evidence is discussed. The results fit into a theory of cerebellar function according to which the cerebellar nuclei are involved in the maintenance of positions.

 

The full text can be found at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC494702/pdf/jnnpsyc00191-0082.pdf.

Copyright © Authors Jürgen C. Aschoff, B. Conrad, and H. H. Kornhuber

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Breakthrough hope for MS treatment

Researchers say they have found how to stop cells from attacking healthy body tissue, a breakthrough that holds hope for MS, diabetes and lupus sufferers.

 

The full news article can be found at Nursing Careers Allied Health.

 

Copyright © AAP 2014

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: NMDA receptor antibodies associated with distinct white matter syndromes

Objective: To report the clinical and radiologic findings of children with NMDA receptor (NMDAR) antibodies and white matter disorders.

This was posted by G.D. on 26th November, 2014. The full text can be found at http://nn.neurology.org/content/1/1/e2.full.

 

Copyright ©  April 24, 2014 |by Yael Hacohen, MRCPCH, et al.

Published in Neurol Neuroimmunol Neuroinflamm June 2014 vol. 1 no. 1 e2

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.