Post Archives

Visitor Survey

Visitor Survey

NAIM

Link: What’s in a NAIM? Hashimoto Encephalopathy, Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis, or Nonvasculitic Autoimmune Meningoencephalitis?

Hashimoto encephalopathy was first described by Lord Brain in 1966.1 Multiple case reports followed and the term Hashimoto encephalopathy became generally accepted for the syndrome of encephalopathy in association with Hashimoto thyroiditis. Although Brain’s original patient with Hashimoto encephalopathy did not improve with corticosteroid treatment, most of the patients described later showed marked improvement with some form of immunosuppression. This has led to the renaming of Hashimoto encephalopathy by some authors as “steroid-responsive encephalopathy associated with autoimmune thyroiditis” (SREAT)2 or “nonvasculitic autoimmune meningoencephalitis” (NAIM), a heterogeneous group that would include autoimmune disorders such as Sjögren syndrome and systemic lupus erythematosus–associated meningoencephalitis as well as Hashimoto encephalopathy. These disorders are unified by the feature of steroid responsiveness.

 

The partial article can be found at http://archneur.jamanetwork.com/article.aspx?articleid=790394.

Copyright © February 2006, Archives of Neurology

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.