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Link: Cognitive and affective dysfunctions in autoimmune thyroiditis

Hashimoto’s thyroiditis (HT) is the most frequent cause of hypothyroidism in areas with sufficient iodine intake. While the impact of thyroid function on mood and cognition is well known, only in the recent years, an increasing number of studies report on the association of HT with cognitive and affective disturbances also in the euthyroid state. Recent imaging studies have shown that these impairments are accompanied by altered brain perfusion, in particular, in the frontal lobe and a reduced gray matter density in the left inferior gyrus frontalis. Brain function abnormalities in euthyroid patients with HT may be subtle and only detected by specific testing or even severe as it is the case in the rare neuropsychiatric disorder Hashimoto’s encephalopathy (HE).

 

The full text could not be located; however, the abstract can be found at http://www.sciencedirect.com/science/article/pii/S0889159114000749.

Copyright © 2014 Elsevier Inc. All rights reserved.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Psychiatric autoimmunity: NMDA-Receptor-IgG and Beyond

Background

Descriptions of psychiatric autoimmunity beyond NMDA-R encephalitis are sparse.

Objective

To report the autoimmune psychiatric spectrum currently recognized in Mayo Clinic practice.

Methods

Chart review, testing of stored serum and CSF for IgGs reactive with synaptic receptors and ion channels, neuronal nuclear and cytoplasmic antigens (including GAD65), and case-control comparison. Patients were: Group 1, all adult psychiatric inpatients tested for neural autoantibodies (2002-2011; n=213); Group 2, all Mayo NMDA-receptor-IgG-positive patients (2009-2013; n=13) and healthy control subjects (n=173).

 

At this time, only the abstract is available online. It can be found at http://www.sciencedirect.com/science/article/pii/S0033318215000043.

Copyright © 2015 Published by Elsevier Inc.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Severe complication of catatonia in a young patient with Hashimoto’s encephalopathy comorbid with Cornelia de Lange syndrome

Dear Editor,

Cornelia de Lange syndrome (CdLs) is a rare genetic disease diagnosed as a cluster of symptoms; however, there are only a few reports mentioning the immunologic problems in patients with CdLs. Hashimoto’s encephalopathy (HE) is an autoimmune encephalitis, which manifests as neurocognitive impairment and elevated antithyroid antibody (ATA) titers. Childhood HE manifests especially as more neuropsychiatric symptoms. However, there are no reports discussing the most severe neuropsychiatric complication, that is, catatonia, in HE. We herein report the first case of a severe complication of catatonia in a patient with HE comorbid with CdLs.

The full text of this “letter to the editor” published in Kaohsiung Journal of Medical Sciences can be found at http://www.kjms-online.com/article/S1607-551X(14)00142-9/fulltext.

Copyright © 2014 Published by Elsevier Inc. | by Yen-Wen Chen, Pi-Lien Hung, Ching-Kuan Wu, and Ping-Tao Tseng

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET

This link leads to the full abstract for a study conducted using FDG-PET scanning for brain amyloid to track the progression of Alzheimer’s Disease. We have been unable to find the full article; however, it can be purchased at Science Direct. The full abstract does provide interesting information for further research, if desired.

Copyright © NeuroImage, Volume 70 15th April, 2013 P. Edison, S.F. Carter, J.O. Rinne, G. Gelosa, K. Herholz, A. Nordberg, D.J. Brooks, R. Hinz

 

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: AutoImmune Encephalitis: Common Symptoms and Diagnostic Workup

An excellent technical video (caution: jargon heavy) which discusses Anti-NMDAR Encephalitis and it’s diagnosis and tretament. Highly recommended viewing for those who are pending a diagnosis of Autoimmune Encephalopathy of any kind as this provides some good information.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Autoimmune Encephalitis: Patient Perspective

This video has been posted by Autoimmune Encephalitis Alliance to their YouTube.com channel. This video features Susanna Cahalan reading excerpts from her book, Brain on Fire.

Shared by G.D. in this post on 23rd October, 2014.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Anti-NMDA Receptor Encephalitis by Chelsea Chisholm

A symposium speech by Chelsea Chisholm. This is regarding my diagnosis of Anti-NMDA Receptor Encephalitis. It is considered a very rare type of autoimmune encephalitis, however, many of the victims believe that it may not be rare, but too often misdiagnosed as psychosis of an unknown cause. Health care members need to be more aware of this condition, as a misdiagnosis can be fatal to the patient. Please note, I am not yet a professional. Information in this speech were provided from my doctors, other whiteness and my medical records. Thank you for listening to my story. – Chelsea Chrisholm

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Voltage-gated Potassium Channel-complex Antibody-associated Limbic Encephalitis

This article discusses antibodies which target the voltage-gated potassium channel complex in the brain. This auto-immune condition effects twice as many men as women, unlike many other auto-immune diseases. It can present with forgetfulness, drowsiness, mood disorders, and generalised or faciobrachial seizures.

The article can be found at http://www.encephalitis.info/information/types-of-encephalitis/types-of-autoimmune-encephalitis/voltage-gated-potassium-channel-complex-antibody-associated-limbic-encephalitis/.

The full text of this article is found at Encephalitis.info and was published in 2014. Copyright © 2014 By Dr Thomas Miller,Clinical Research Fellow, University of Oxford, John Radcliffe Hospital, Oxford

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Steroid-responsive Encephalopathy in Autoimmune Thyroiditis: Clinical Spectrum and MRI Observations in Three Cases

This study looks at three cases of Hashimoto’s Encephalopathy, discussing MRI and EEG observations in each case. To read the full text, proceed to http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077662/.

The full text of this article is found at PMC and was published in 2011. Copyright © Annals of Indian Academy of Neurology

 

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Hashimoto’s Encephalopathy Presenting with Progressive Cerebellar Ataxia

This study discusses a 41 year old female with multiple neurological complaints. It further suggests that Hashimoto’s Encephalopathy should be included in the differential diagnosis of a treatable ataxia. To read the full text, proceed to http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077662/.

The full text of this article is found at PMC and was published in 2007.

Copyright © 2007 BMJ Publishing Group Ltd

 

 

 

 

 

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.