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NMDAR

Link: High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types

To retrospectively determine the frequency of N-Methyl-D-Aspartate (NMDA) receptor (NMDAR) autoantibodies in patients with different forms of dementia.

This full text discusses the discovery of NMDA antibodies in those with dementias. The text can be found at http://onlinelibrary.wiley.com/doi/10.1002/acn3.120/full.

© 2014 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Rethinking therapy decisions in autoimmune encephalopathy

Researchers say that diagnosis and management of encephalopathies may need to be rethought, as many patients who test negative for the relevant antibody still benefit from immunotherapy.

Of 48 patients with a diagnosis of probable autoimmune encephalopathy, only 21 (44%) individuals were positive for antibodies known to be associated with this type of encephalopathy. However, both antibody-positive and antibody-negative patients responded to immunotherapy, with complete recovery achieved in 20 (42%) children, after a mean follow-up period of 24 months.

The full article can be found at http://linkis.com/www.news-medical.net/oSP1E.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Dr. Josep Dallmau

Josep Dalmau

Unknown affiliation
Verified email at uphs.upenn.edu
Dr. Dalmau’s current published works can be found at https://scholar.google.co.uk/citations?user=Sr8izWkAAAAJ&hl=en&oi=sra.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Anti-NMDAR encephalitis misdiagnosed as Hashimoto’s encephalopathy

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a well-defined autoimmune disorder. Hashimoto’s encephalopathy (HE) is a still controversial entity, lacking definite diagnostic criteria.

This study discusses a paediatric case of Autoimmune Encephalopathy with presentation similar to Hashimoto’s Encephalitis. The abstract only can be found at http://www.sciencedirect.com/science/article/pii/S1090379813001256. This article is only available by subscription or purchase.

 

Copyright © 2013 European Paediatric Neurology Society. | Published by Elsevier Ltd.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Autoantibody-Associated Movement Disorders

Autoantibodies to the extracellular domain of neuronal proteins cause different neurological conditions with movement disorders as a prominent feature. We reviewed the literature of autoantibody-mediated and autoantibody-associated diseases focusing on anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, autoimmune basal ganglia encephalitis, Sydenham chorea, and the rare syndrome of progressive encephalomyelitis with rigidity and myoclonus.

The full text is available by subscription to Thieme E-Books and E-Journals. The abstract  can be found at https://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1358603.

 

Copyright © Thieme Neuropediatrics January 1st, 2013 | Shekeeb S. Mohammad, Sudarshini Ramanathan, Fabienne Brilot, Russell C. Dale

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

PDF Link: Autoimmune encephalitis – History & current knowledge

This PDF link will take you to a PDF published by PANDAS Network and has a wealth of information about auto-immune diseases.

 

Introduction
The acute fulminating epidemic form of encephalitis lethargica (von Economo, EL) seems to have
disappeared, since there have been no further reported epidemics after 1916-1927. During that period of
time, both rheumatic fever (RF) and Sydenham chorea (SC) were associated with and later proven to be
provoked by streptococcal infections. The occurrence of RF including SC has become much less frequent in
the industrial world.

The full text can be found in a PDF at http://pandasnetwork.org/wp-content/uploads/2013/07/Autoimmune_encephalitis.pdf

 

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Autoimmune Encephalitis: Patient Perspective

This video has been posted by Autoimmune Encephalitis Alliance to their YouTube.com channel. This video features Susanna Cahalan reading excerpts from her book, Brain on Fire.

Shared by G.D. in this post on 23rd October, 2014.

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Video: Anti-NMDA Receptor Encephalitis by Chelsea Chisholm

A symposium speech by Chelsea Chisholm. This is regarding my diagnosis of Anti-NMDA Receptor Encephalitis. It is considered a very rare type of autoimmune encephalitis, however, many of the victims believe that it may not be rare, but too often misdiagnosed as psychosis of an unknown cause. Health care members need to be more aware of this condition, as a misdiagnosis can be fatal to the patient. Please note, I am not yet a professional. Information in this speech were provided from my doctors, other whiteness and my medical records. Thank you for listening to my story. – Chelsea Chrisholm

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Cell-surface central nervous system autoantibodies: Clinical relevance and emerging paradigms

This article discusses the recent finding of pathogenic auto-antibodies which appear to go hand-in-hand with Central Nervous System (CNS) diseases which respond well to immunologic treatment.

To read the full text, proceed to http://onlinelibrary.wiley.com/enhanced/doi/10.1002/ana.24200/

The full text of this article is found at Willey.com and was published in 2014. Copyright © 2014 American Neurological Association

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This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Antibody-Mediated Epilepsies

This study discusses the presence of antibodies against the neuronal surface proteins which lead to drug-resistent epilepsies. These epilepsies respond to immunologic therapies. Most of the article can be found at this link. Unfortunately, the rest of the article is available to subscribers only.

The article can be found at http://www.medlink.com/cip.asp?UID=mlt002s5&src=Search&ref=40036726.

The article is found at Medlink.com. Copyright © 2011.

Is there a tag missing? Please comment below.

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.