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Link: Encephalitis Related research projects @ January 2014 (PDF)

This link leads to a listing of UK Encephalitis studies in 2014. This information is provided for research purposes only.

 

http://www.encephalitis.info/files/4414/0731/3048/Research_Projects_2014.pdf

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Proposal for Discovering SNPs from Eight Commonly Used Inbred Rat Strains

Importance of the organism:

The importance of the laboratory rat in biomedical research is well established. Since 1966, there have been on average over 28,000 publications per year using rat (PubMed search, key word: rat); in the last eight years (1996-2003) there have been on average almost 37,000 publications annually. The initiation of the rat genome project has yielded a tremendous wealth of genomic resources including genetic maps; radiation hybrid (RH) cell lines and the associated RH maps (over 6,000 genetic markers and 16,000 genes and ESTs mapped); cDNA libraries generating more than 593,880 ESTs (with more being generated) clustered into over 63,000 UniGenes; over 10,033 genetic markers; and a published draft (~6.8 X) sequence of the genome based on the inbred BN (Brown Norway) strain. The physiology of the “sequenced” rat is being explored by placing each chromosome of the BN on to two genomic backgrounds (the SS and FHH strains) and then measuring over 200 phenotypes in each strain. The consomic rats and the data are available from the PhysGen Programs in Genomic Applications (PGA) project. The rat genome resources have also been expanded by three new BAC libraries (the F344, SS, and FHH) via the BAC resource White Paper proposal. Over 700 strains of rats, including over 200 transgenic lines, numerous congenics, advanced intercross lines, and recombinant inbred panels exist and are being actively used to advance the annotation of the human genome. This single nucleotide polymorphisms (SNP) project is needed to advance these studies. The rat is primarily known as a physiological model and there has been some question over the years about the likelihood that the rat genomic tools would be fully utilized. Figures 1 and 2 show the change in usage of the Rat Genome Database website (measured by number of pages accessed) and changes in the number of visits (defined as 30 minutes using the site without more than 5 minutes of inactivity), over the period 2000-2004. Recall that an advanced draft of the rat genomic sequence, together with an analysis and annotation, was published in April 2004 (Rat Genome Sequencing Project Consortium, 2004).

The full PDF text of this interesting article from genome.gov can be found at http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/RatSNPSeq.pdf.

 

Copyright © Authors Tim Aitman, Richard Gibbs, George Weinstock, Norbert Huebner, Michael JensenSeaman, Daniel Maloney, and Howard J. Jacob

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: A NEUROLOGIST’S GUIDE TO USING ICD-9-CM CODES FOR CEREBROVASCULAR DISEASES

ICD-9-CM codes for cerebrovascular diseases is not “user friendly”. This
presentation is designed to assist neurologists in choosing proper ICD-9-CM
codes by using a cross-walk to more familiar terms. The user is strongly
encouraged to re-refer to ICD-9-CM Volume 1 after choosing a code here to be
sure there are no other instructions which would indicate using a different code
for this situation.

This is a PDF guide, A NEUROLOGIST’S GUIDE TO USING ICD-9-CM CODES FOR CEREBROVASCULAR DISEASES, as a tool for helping neurologists code files indicating the correct diagnosis/syndromes. This appears to be applicable for the United States only. This is linked to for research and educational use.

 

Copyright © American Brain Foundation 2014

 

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients’ antibodies react with the N-terminal domain of the GluN1 (previously known as NR1) subunit of NMDAR causing in cultured neurons a selective and reversible internalization of cell-surface receptors. –

 

This was shared by G.D. on 25th November, 2014. To read the full text, proceed to http://brain.oxfordjournals.org/content/early/2014/11/11/brain.awu310.

The full text of this article is found at Oxford University Press and was published in May of 2011. Copyright © 2014 Oxford University Press

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Protected: Link: Template Case Study

There is no excerpt because this is a protected post.

Link: Evaluating Cancer Information on the Internet

This article discusses evaluating information found online for accuracy and credibility in order to ensure that patients are reviewing information relevant and valuable to their circumstances. This article discusses this topic in relation to cancer information but can be applied to other illnesses as well. To read the full text, proceed to http://www.cancer.net/research-and-advocacy/introduction-cancer-research/evaluating-cancer-information-internet?utm_source=September+2014&utm_campaign=September+2014&utm_medium=email.

The full text of this article is found at Cancer.net and was published in 2012. Copyright © 2012 American Society of Clinical Oncology (ASCO) – Cancer.Net

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.