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thyroiditis

Link: Antithyroid antibody-linked symptoms in borderline personality disorder

Circulating thyroid autoantibodies are more prevalent in patients with mood disorders than in the general population, but longitudinal clinical data that establish a relationship between thyroid antibody status and the course of any psychiatric syndrome have been lacking. In addition, scant attention has been paid to thyroid hormones and autoimmunity in borderline personality disorder (BPD). We report a case of a patient with classic BPD whose fluctuating mood and, especially, psychotic symptoms—rated using a double-blind method—were directly linked to antithyroglobulin antibody titers serially determined over an inpatient period of 275 d.

The abstract and first page can be found at http://link.springer.com/article/10.1385/ENDO:21:2:153.

Copyright © Endocrine July 2003 | Authors Dr. Thomas D. Geracioti Jr., Mitchel A. Kling, Robert M. Post, Philip W. Gold

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.

Link: Hashimoto’s encephalopathy mimicking presenile dementia

Abstract

Hashimoto’s encephalopathy (HE), which carries kaleidoscopic clinical presentations, is easily misdiagnosed in clinical practice. Early diagnosis and prompt initiation of steroid therapy are associated with good prognosis. We describe a 50-year-old female patient who had subclinical hypothyroidism and who presented herself with gradual cognitive impairment, accompanied with auditory hallucination and delusion. Increased anti-thyroid antibodies titers were found in her serum and cerebrospinal fluid. The HE diagnosis was confirmed using the laboratory test for anti-thyroid antibodies along with the patient’s clinical presentation. We treated her with steroid pulse therapy, and the results were favorable. We highlight this case to call for early diagnosis and prompt intervention of HE in clinical practice.

The full text can be purchased from Science Direct. This study was published in General Hospital Psychiatry.

 

Copyright © 2014 Elsevier Inc. | General Hospital Psychiatry Volume 36, May/June 2014, Page 360

This website is not a substitute for independent professional advice. Nothing contained in this site is intended to be used as medical advice. No articles, personal accounts, or other content are intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professionals advice.